CB – Cesar Azpilicueta
With Trevoh Chalobah and Andreas Christensen both sidelined with injuries, and Thiago Silva likely to be rested, the club captain is expected to slot back into the right-sided centre-back position.
Azpilicueta did not cope that well with Sadio Mane at the weekend, and he will face another big test tomorrow when he comes up against either Son Heung-min or Steven Bergwijn.